round button
Categories
How To Order | Shipping Policy | FAQ | Contact Us

Customer Support: +18102015692
Refer Friend

Tadalafil Tablets
♂ Cialis Black

  • Cialis Tablets
  • BRD007
  • In Stock

Premium High Quality Product & Original Active Substance!

Select Doses:

   Manufacturer's Suggested Retail Price (MSRP) per pill is $3.55 ! Buying from us will save you at least 36.34%

Package per pill Price SAVINGS BONUS Order
800mg * 30 pills
$2.26 $67.80 $0.00
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount
800mg * 60 pills
$2.01 $120.60 $15.00
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount
800mg * 90 pills
$1.89 $170.10 $33.30
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount
800mg * 120 pills
$1.61 $193.20 $78.00
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount
800mg * 150 pills
$1.43 $214.50 $124.50
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount
800mg * 180 pills
$1.29 $232.20 $174.60
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount

Tadalafil is an orally administered drug used to treat male erectile dysfunction (impotence). It is marketed worldwide under the brand name Cialis. It is a phosphodiesterase 5 (PDE5) inhibitor.

Tadalafil's distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the "weekend pill." This longer half-life also is the basis of current investigation for tadalafil's use in pulmonary arterial hypertension as a once-daily therapy.

Tadalafil tablets are indicated for the treatment of: erectile dysfunction (ED), the signs and symptoms of benign prostatic hyperplasia (BPH), the signs and symptoms of BPH (ED/BPH).

Black Cialis has been storming the market for a long time and managed to attract attention from a very wide audience of customers. Men all over the world choose Black Cialis to treat their issues related to erection and sexual performance in general. With the strength of 20 regular Cialis pills, black tablets with the 800mg written on them bring a lot of joy to millions of men and women all over the world. There are virtually no negative downsides to using Black Cialis. It is a medication that has been around for a long time. Tadalafil has been tested by thousands of professionals of different occupations and from various scientific backgrounds. This is truly a very effective ED drug that deservingly should be in the center of attention.

Tadalafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum.

This then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased inflow of blood and an erection. Tadalafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum.

This means that, with tadalafil on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, tadalafil should not cause an erection.

Tadalafil inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle.

This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by tadalafil enhances erectile function by increasing the amount of cGMP.

Metabolism: Tadalafil is predominantly metabolized by CYP3A4 to a catechol metabolite. The catechol metabolite undergoes extensive methylation and glucuronidation to form the methylcatechol and methylcatechol glucuronide conjugate, respectively. In vitro data suggests the metabolites are not expected to be pharmacologically active at observed metabolite concentrations.

Absorption: After single oral-dose administration, the maximum observed plasma concentration (Cmax) of tadalafil is achieved between 30 minutes and 6 hours (median time of 2 hours). Absolute bioavailability of tadalafil following oral dosing has not been determined.

Route of elimination: Tadalafil is excreted predominantly as metabolites, mainly in the feces (approximately 61% of the dose) and to a lesser extent in the urine (approximately 36% of the dose).

Half life: 17.5 hours

All medicines may cause side effects, but many people have no, or minor, side effects.Some medical conditions may interact with Tadalafil.

Tell your doctor or pharmacist if you have any medical conditions.

Common tadalafil side effects may include: headache, flushing (warmth, redness, or tingly feeling), nausea, upset stomach, stuffy nose; or muscle pain, back pain, pain in your arms or legs.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Shannon
06/Aug/2024

Got prescription from doc, couple of pills very expensive! Bought Cialis Black 800mg from here, much much more effective. Take 400mg each day, erection only when stimulated, very hard and at my full length. Can perform for as long as I want. Am 62 and it's great. Great drug, happy and smiling wife, happy man.

Lilly
04/Aug/2024

I'm 52 and my partner is 44. He has had some difficulty with full erections on and off his whole life. For a while now, it has been more marshmallow than wood. Things have declined. I encouraged him to see his doctor and he bought the Cialis Black 800m. As a result, we have just tried the very first 800 mg tab. Result? Incredible erection, great sex for us both, and most important - he feels like himself. He doesn't feel like something strange has taken over his experience. Nothing artificial about it. More like being restored. And no side effects so far. We are both very pleased.

Lear
21/Dec/2023

I use Cialis Black 800mg, take one tablet, usually an hour to 3 hours before intercourse. What a difference this has truly made in our lives. We had gone 2 plus years without real sex, mostly just foreplay. Now, with Cialis Black, I am rock hard like my younger days and can go for hours. I always wake up with a pitched tent the next morning. Sometimes I do wake up with a mild head ache as a side effect but that is really all.

Nik
27/Oct/2023

Cialis Black is amazing. I prefer it over Levitra and Viagra. I tried everything. Cialis Black makes you rock hard. Believe me, this is not an ad. I don't care what you buy, just my own experience. Side effects, bit of a rush in your face, ear noise, mmm that's it.

Marc
09/Mar/2023

Hello I'm 43 years old married for 12 years now. And about 3 years ago I got hit with erectile dysfunction pretty bad. And I found out about Tadalafil and since then my love life has been better than ever. I'm ready to get busy in a second I don't know what I would do without it. And my wife she knows about it and she tells me to take it easy because of the Very Firm erections it produces.

Write a review

Note: HTML is not translated!
    Bad 
 
 
 
 
 Good
TOP
a